Understanding Synovial Fluid and Knee Function
The knee joint is cushioned and lubricated by synovial fluid, a clear, viscous liquid that reduces friction between cartilage surfaces. The key component of this fluid is hyaluronic acid, a naturally occurring substance responsible for maintaining the joint's viscoelasticity and shock absorption capacity.
However, in people with osteoarthritis, the quality and quantity of synovial fluid deteriorate over time. The reduced viscosity of the fluid leads to increased joint friction, stiffness, and pain. As a result, patients often experience limited mobility and a decline in quality of life.
What Is a Synovial Fluid Injection?
A synovial fluid injection, also known as viscosupplementation, involves injecting hyaluronic acid directly into the knee joint. The purpose is to restore the natural lubrication of the joint and relieve symptoms of osteoarthritis.
Medical-grade HA injections-like SingJoint® Medical Sodium Hyaluronate Gel-act as a supplement or replacement for the degraded synovial fluid. This therapy provides both mechanical cushioning and biological benefits, such as reducing inflammation and stimulating the body's own HA production.
How Synovial Fluid Injections Work
When administered into the joint cavity, exogenous HA binds to receptors on synovial fibroblasts and cartilage cells, stimulating the synthesis of endogenous hyaluronic acid and inhibiting inflammatory mediators.
The result is a restoration of joint homeostasis, improved viscosity of synovial fluid, and enhanced protection of the cartilage. Studies show that viscosupplementation can help:
- Relieve pain and stiffness
- Improve joint mobility
- Delay the need for total knee replacement
- Reduce inflammation and cartilage degradation
These injections are most beneficial for patients with mild to moderate osteoarthritis, providing relief for up to six months depending on the product's formulation and molecular weight.
When to Consider a Synovial Fluid Injection for Knee Pain
You may be a candidate for a synovial fluid injection if you:
- Have persistent knee pain due to osteoarthritis despite using pain relievers or physical therapy.
- Experience swelling, stiffness, or grinding sensations in your knee joints.
- Want to delay or avoid knee replacement surgery.
- Are looking for a non-surgical, long-lasting option for pain relief.
Doctors typically recommend this procedure when conservative treatments such as rest, weight control, and oral medications no longer provide sufficient relief.
What to Expect During the Procedure
The injection process is relatively simple and minimally invasive:
- The doctor cleans and sterilizes the knee area.
- Any excess fluid in the joint may be aspirated.
- The hyaluronic acid gel is then injected directly into the synovial cavity.
- The patient may be advised to rest briefly before resuming normal activity.
Treatment plans vary-some patients benefit from a single high-concentration injection, while others undergo a series of 3–5 weekly injections. The effects typically begin within a few weeks and may last up to six months or more.
Why Choose SingJoint® Medical Sodium Hyaluronate Gel
SingJoint®, developed by Hangzhou Singclean Medical Products Co., Ltd., is a non-animal sourced, bio-fermented hyaluronic acid gel designed specifically for viscosupplementation. It offers several key advantages:
- Excellent Biocompatibility: Produced via microbial fermentation, ensuring no immunogenic reactions.
- High Concentration & Molecular Weight: Replicates the natural viscosity of healthy synovial fluid, creating better lubrication and shock absorption.
- Long-lasting Pain Relief: Provides sustained comfort and function for up to six months.
- Convenient Administration: Suitable for both single and multiple injection regimens.
With its European Pharmacopoeia compliance, Class 10,000 cleanroom production, and proven clinical performance, SingJoint® is trusted by healthcare professionals worldwide.
Learn more about our innovative viscosupplementation solutions at SingJoint® Medical Sodium Hyaluronate Gel.
About Singclean Medical
Founded in 2003, Hangzhou Singclean Medical Products Co., Ltd. is a manufacturer of hyaluronic acid-based medical products for orthopedic, ophthalmic, and aesthetic applications. With more than 20 years of R&D expertise, Singclean adheres to strict ISO and CE standards to ensure product safety, purity, and efficacy.
The company's orthopedic line, including SingJoint®, reflects Singclean's commitment to biocompatible, safe, and effective medical innovations that enhance patient comfort and mobility worldwide.
