Singderm Hyaluronic Acid Filler With Lidocaine
Singderm® consists of modified hyaluronic acid (HA) produced by bacteria and 0.3% lidocaine, formulated to a concentration of 24mg/ml in a physiologic buffer.
• Singderm®, being animal-origin free, consists of modfied hyaluronic acid (HA) produced by bacteria, formulated to a concentration of 24 mg/ml and 0.3% lidocaine in a physiologic buffer, presented in a pre-filled, disposable BD syringe.
• Indicated for injection into the mid to deep dermis or subcutaneous for correction of mid or deep depressions of the skin, as well as for correcting age-related volume deficit.
Singderm Advantages
Effective: Produced by SingLink® unique patented cross-linking technology to obtain a high viscosity smooth, uniform gel, helps achieve a natural looking
Comfortable: Add 0. 3% lidocaine, creating more comfortable and painless experience
Long-lasting: Excellent biocompatibility, slower degradation rate, effectiveness rate is 92.7% at 12 months
Specification
| Cross-linked agent | DVS | |
| Formulation process | Mono-phasic | |
| Concentration | 24mg/ml | |
| Composition | Hyaluronic acid and 0.3% lidocaine | |
| Specification | 1ml | 10ml |
| Depth of Injection | Middle or deep of dermis | |
| Duration | More than 12 months | |
Temple
Nasolabial Folds
Nose
Cheek
Lip Volume
Marionette Lines
Jawline Sculpting
Chin Remodeling
Singderm Data
The actual concentration of cross-linked HA was measured by the filter paper filtration method
High Concentration of Cross-linked HA to achieve good filling and lifting effect
|
Content mg/ml |
Singderm® |
***M (International brand) |
***X (Chinese Brand) |
|
HA Content |
24 |
24 |
20 |
|
Cross-linked HA |
20.8 |
15.6 |
8.8 |
|
non cross-linked HA |
3.2 |
8.4 |
11.2 |
•The efficacy rate is measured by wrinkle severity rating scale(WSRS) from baseline.
•This clinical trial being a self-controlled study was performed in three clinical sites, 100 subjects participated.
Singderm® effectiveness rate is 92.7% at 12 month while currently the highest 12-month effectiveness rate of the internationally well-known dermal filler is 83%.
Comparison Between DVS And BDDE
|
Comparison options |
DVS Divinyl Sulfone, C4H6O2S |
BDDE Butanediol Diglycidyl Ether, C10H18O4 |
|
Chemical reaction rate |
Fast |
Slow |
|
Intramolecular and |
Reactions at the level of several vinyl groups with the formation of a high level of internal and intermolecular crosslinking |
A more detected molecular cross-linking |
|
The distance between the HA chains after crosslinking |
Close distance between molecules, |
Greater distance between molecules |
|
Cross Link Level |
The reaction level is up to 99%. Dense mesh formation with more stable particles and prolonged stereometry |
After reaction with ha, the BDDE |
|
Conclusion |
DVS, the stable hydrogels containing sulfonyl-bis-ethyl linkage can hold higher weight of HA molecules. The HA-DVS-HA hydrogel is already strong after 15 minutes comparing other agents. |
|
Smooth Delivery
An Innovative Glass Pre-fillable Syringe
BD Hylok™ Designed for the Administration of Hyaluronic Acid
video Introduction
Our Certificate
ISO
CE
CFS
FAQ
Q: 1: Can I have a sample for our testing?
A: 1: Yes, stock samples are available and but you need to pay the freight.
Q: 2: What is sample ready time?
A: 2: Usually 3-5 days, since it was produced against specific demands to guarantee most freshness.
Q: 3: What about the payment methods?
A: 3: Paypal, Western Union, T/T
Q: 4: What's your delivery time?
A: 4: Usually 5-35 days after receiving the deposit.
Q: 5: What's your MOQ of each product?
A: 5: Lowest MOQ but price is different for different quantity. If you have large quantity, please kindly contact us for charming price.
Q: 6: How to deal with the products regarding the quality and quantity?
A: 6: Singclean medical is a professional supplier for the medical products for many years. it is of great importance for the quality issues, QC department will arrange the checking every lot, also we have the spot checking at random, we keep high concentration of quality issues, also quantity issues , which is the life of a company, we already got CE, ISO, SGS and FSC certification.
Q: 7: Can I have a phone call directly with your sales if some urgent questions?
A: 7: yes, of course, that is wonderful to save the time and catch the key point easily. our sales team members can speak fluent SPANISH, RUSSIAN, GERMAN, JAPANESE, ENGLISH. If you have any questions, you can call us or send us by email.
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