Hyaluronic Acid Dermal Filler
Our Advantage
Hangzhou Singclean Medical Products Co., Ltd., established in 2002 with registered capital of 80,000,000 RMB, is a national high and new technology enterprise integrating the R&D, production and sales of medical biomaterials. With highly-qualified staff, thorough quality management system and first-class facilities, the company ensures the continuous production of medical devices of Class III that conform to the laws and regulations of NMPA and EU MDR.

Quality Certified
Factory with CE, ISO13485, BGMP & MDSAP certification. Production equipment and processes complying with international standards. Obtained local registration in 50+ countries including EU countries, Singapore and other countries.
Global Supply
Accept ODM/OEM service. We sold products to over 60 countries and regions. More than 330 global partners’ trust! Sales channels cover 120+ countries and regions!


Customer Satisfaction
Our success lies not only in production and R&D but also in our attention to our customers. We have established long-term relationships with our customers and continuously meet their expectations by providing excellent products and quality services. Customer satisfaction is one of our most important metrics. We supply 24/7 Professional Support, deliver instantly.
Strong Factory Strength
28,000 square meters international intelligent manufacturing base. Expansion of 20,000 square meters of complex building. With 900 square meters of cross-linked sodium hyaluronate gel workshop-class 10,000 cleanroom.

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Singfiller Dermal Filler For Anti-Aging With CESingfiller is a colorless, transplant, viscous cross-linked acid filler for facial injection. It can be injected into the dermis to supplement the hyaluronic acid of our faces and reduce the...read more
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Singderm Hyaluronic Acid Filler With LidocaineSingderm Hyaluronic Acid Filler With Lidocaine,consists of modified hyaluronic acid(HA) produced by bacteria and 0.3% lidocaine, formulated to a concentration of 24mg/ml in a physiologic...read more
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Poly L Lactic Acid FillerProduct: Singderm Injectable PLLA Filler Function:Collagen Regeneration Application:Temple, Nasolabial folds, Cheek, Jawline, Chinread more
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PDRN Skin BoosterWholesale SKformula PDRN Skin Booster,improving skin elasticity and structureread more
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Sodium Hyaluronate Complex Solution With Amino AcidsSKformula odium Hyaluronate Complex Solution with Amino Acids, One solution for hyadration, skin density and elasticity improvingread more
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SKformula PDRN FillerSKformula PDRN Filler Wanting to remove the traces of time of your skin? Having the need of moisturizing, brightening skins and improving skin elasticity? We find the key to stimulate the...read more
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Singderm PLLA Poly L Lactic Acid FillerProduct: Singderm Injectable PLLA Filler Function:Collagen Regeneration Application:Temple, Nasolabial folds, Cheek, Jawline, Chinread more
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Singderm Injectable PLLA FillerProduct: Singderm Injectable PLLA Filler Function:Collagen Regeneration Application:Temple, Nasolabial folds, Cheek, Jawline, Chinread more
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Dermal Filler For Remove Frown LinesSingderm 24mg/ml hyaluronic acid dermal filler for remove frown lines with painless injection experienceread more

Singfiller cross-linked sodium hyaluronate gel for plastic surgery is a sterile, transparent gel of stabilized hyaluronic acid of origin. Singfiller is a filler that adds volume to the tissue, thereby restoring the skin contours or enhancing the lips to the desired level of correction. The concentration of hyaluronic acid is 20mg/ml. We supply 5 different formats for different area injection: Fine, Derm, Deep, Deeper and Sub-Q.
Singfiller FINE is intended for frown lines, cheek lines, crow's feet, wrinkles across the forehead, necklines and nose.
Singfiller Bi-phasic Dermal Filler DERM is intended for wrinkles across the forehead, neck lines, nose, chin, lip and earlobe.
Singfiller DEEP is intended for nasolabial folds, chin, lip, earlobe, temple and cheek.
Singfiller DEEPER Cross-Linked Dermal Filler is intended for nasolabial folds, temple and cheek.
Singfiller SUB-Q Hyaluronic Acid Filler is for breast enhance and butt enlargement.
Advantages of Singfiller bi-phasic dermal filler
1
Raw material hyaluronic acid comes from bacterial fermentation, no pyrogen, no rejection reaction, good biocompatibility, etc. Singfiller’s non-animal origin HA is JP (Japanese Pharmacopoeia) or EP (European Pharmacopoeia) approved.
2
Crosslinking more evenly, high viscoelastic index.
3
Strong cohesion, hard to shift and spread.
4
Perfect shaping, deformation resistance.
5
Granulation is more uniform. The degree of swelling is more reasonable.
6
A consistent and even extrusion force allows smooth injection.

Singderm® Mono-phasic Dermal Filler is a sterile, biodegradable, nonpyrogenic, viscoelastic, clear, colorless, homogenized gel implant. Mono-phasic Dermal Filler consists of modified hyaluronic acid (HA) produced by bacteria, formulated to a concentration of 24 mg/ml and 0.3% lidocaine in a physiologic buffer. Indicated for injection into the mid to deep dermis or subcutaneous for correction of mid or deep depressions of the skin, as well as for correcting age-related volume deficit.
Singderm® Silk injectable gel is indicated for injection into the lips for lip augmentation and for correction of perioral rhytids in adults over the age of 18.
Singderm® Lift Mono-phasic Dermal Filler is indicated for deep (subcutaneous and/or supraperiosteal) injection for cheek augmentation to correct age-related volume deficit in the midface in adults over the age of 18.
Advantages of Singderm mono-phasic dermal filler
Reliable HA raw material
Singclean's non-animal origin HA is JP (Japanese Pharmacopoeia) or EP(European Pharmacopoeia) approved.
Safety
With good biocompatibility, the osmotic pressure and PH value are close to the human body, minimizing redness and swelling.
Good Filling Effect
High viscoelasticity to achieve a good filling effect, not easily to shift and deform, offers strong supporting force to effectively improve uneven skin tone, enhance face shape and bring perfect and natural facelifts.
Long-lasting Effect
The high concentration HA of 24mg/ml and SingLink cross-linked technology guarantee a long-lasting effect that can last more than 12 months. Singderm effectiveness rate is 92.7% at the 12th month.
Pleasant and Painless Experience
Singderm® Mono-phasic Dermal Filler is a mono-phasic, smooth and homogeneous gel, soft in texture without foreign body sensation.
0.3% lidocaine and evenly cross-linking giving the better experience of slight pain or even no pain.
Special SingLink® Technology
SingLink®, Unique Patented Cross-linking Technology. Form mono-phasic, smooth and homogeneous gel, contain no particles, soft texture without foreign body sensation.
New launched dermal filler products
Singmeso® Sodium hyaluronate solution for injection (light cross-inked) is a kind of gel-like solution prepared by mild crosslinking modification. It can be injected into the dermal tissue of the skin to improve the skin condition, moisturize and lighten the skin, and smooth fine lines. It has the advantages of mildly modified, natural raw materials, excellent biocompatibility, safe and reversible.
SingRejuve®Injectable emulsified cross-linked sodium hyaluronate gel is for mid-to-deep facial dermal tissue injection to correct moderate to severe naso-lip wrinkles. Emulsification process forms particles, cross-linking solidifies particle morphology
Uniform particle size (~80-150μm). The concentration is 18mg/ml. It is for improving skin contours, smooth wrinkles and folds, eliminating skin depressions and enhance skin aesthetics. It has the advantages of highly stretchable, excellent cohesion, smooth and easy to inject.
Singsumile® injectable PLLA filler can stimulates collagen regeneration for nasolabial areas. With the increase in age, skin cell vitality diminishes, collagen gradually decreases, and aging symptoms such as "depression," "looseness," and "sagging" appear on the skin. Singsumile injectable PLLA filler is for solve these skin problems. With PLLA in it, it can continuous stimulation for collagen regeneration.
Singsumile has the advantages of naturally long-lasting, safe stimulation of autologous cells to achieve significant results. One month's waiting for up to 18~24 months' youth!
What is the advantages of hyaluronic acid dermal filler?
Hyaluronic acid dermal fillers have several advantages for application in the field of aesthetic medicine:
Natural Substance: Hyaluronic acid is a natural substance in human body, so it is biocompatible and well-tolerated for people.
Hydration and Volume: hyaluronic acid has the ability to attract and retain water molecules, providing hydration and adding volume to the skin. So hyaluronic acid can help to improve the appearance of fine lines, wrinkles, and areas with volume loss.
Versatility: HA fillers are versatile and can be used for various aesthetic concerns, including smoothing wrinkles, enhancing lips, restoring facial volume, and contouring specific facial features.
Immediate Results: The results of hyaluronic acid injection can be see immediately after the treatment, providing quick and noticeable improvements, no need too much extra time to wait.
Customizable Treatment: HA fillers come in various formulations with different particle sizes and concentrations. It means medical beauty professionals can choose right kind of hyaluronic acid filler depend on peoples’ need.
Reversibility: In case of dissatisfaction or complications, hyaluronic acid fillers can be partially or fully reversed using an enzyme called hyaluronidase. This offers an extra level of safety and control.
However, though hyaluronic acid filler has so many advantages, it is still important to know that individual responses to dermal fillers may vary, and the choice of filler depends on the specific aesthetic goals, the area being treated, and the patient's unique characteristics. What’s more, different injection methods will also lead to different injection results. So before using the hyaluronic acid dermal filler, please check many factors.
What is the difference between bi-phasic dermal filler and mono-phasic dermal filler?
Bi-phasic and mono-phasic dermal fillers are terms used to describe different formulations of injectable substances used in cosmetic procedures to enhance facial features, restore volume, and reduce the appearance of wrinkles. The main difference between the two lies in their composition and how they behave within the skin.
Mono-phasic Dermal Fillers:
Composition: Mono-phasic fillers have a uniform composition throughout. They consist of a single phase, typically a gel-like substance. The shape of monophasic hyaluronic acid is like a smooth and homogeneous cross-linked gel, similar to jelly.
Texture: These fillers have a smooth and consistent texture.
Injection: Mono-phasic fillers are injected into the targeted area in a single, uniform manner. They provide immediate volume and correction upon injection.
Application: Shaping, nose/chin enhancement, face lift, filling deep wrinkles, lines.
Bi-phasic Dermal Fillers:
Composition: Bi-phasic fillers have a two-phase composition. They contain both a gel-like substance and microspheres or particles suspended within the gel. Bi-phasic hyaluronic acid is shaped like a mixture of cross-linked particles and non-cross-linked liquids, like sago dew.
Texture: The gel phase provides immediate volume upon injection, while the microspheres or particles contribute to longer-term structural support.
Injection: Bi-phasic fillers are injected similarly to mono-phasic fillers, providing immediate results from the gel phase and longer-term benefits from the microspheres.
Application: Suitable for injection nasolabial furrows, lacrimal furrows, lips, skin surface wrinkles and other parts requiring high filling effect.
The choice between bi-phasic and mono-phasic fillers depends on factors such as the specific aesthetic goals, the area being treated, and the duration of results desired. Both has its advantages, we should choose it depend on our needs.
What is PLLA? What is the future of PLLA application in medical aesthetic industry field?
PLLA stands for Poly-L-Lactic Acid, which is a biodegradable and biocompatible synthetic polymer. It is a biodegradable material with good bioabsorption and biocompatibility. After degradation in the body, L-lactic acid is produced, which is a substance in the human body, so it has no side effects on the human body.
At present, the main applications are medical surgical sutures, drug delivery carriers, tissue engineering scaffoles, bone anchors/bone nails, etc. In the field of medical beauty, PLLA injection is often referred to as "baby beauty injection", PLLA is commonly used in dermal fillers to stimulate collagen production and promote skin tightening.
The outlook for PLLA in the medical aesthetics industry is promising. PLLA has gained popularity due to its ability to provide gradual and natural-looking results by stimulating the body's collagen production over time. It is known for its longevity and effectiveness in treating volume loss and wrinkles.
PLLA dermal fillers are often used for facial rejuvenation, addressing concerns such as nasolabial folds, marionette lines, and overall skin laxity. As a bio-stimulatory filler, PLLA helps improve skin texture and firmness by encouraging the growth of new collagen fibers.
Since collagen of human body gone gradually as people aging, skin problems including wrinkles, fine lines will appear. Stimulate the growth of new collagen fibers will effectively solve these skin problems.
Overall, PLLA's future in the medical aesthetics field seems positive, with a continued interest in its collagen-stimulating properties and its potential for long-lasting aesthetic improvements. After the application of PLLA, the treatment effects will appear gradually.
How to cooperate with us?
Submit inquiry
You can send inquiries to us via email or other channels, providing your requirements and relevant information. Our professional team will respond promptly, offering detailed product information and quotations.
Assignment of sales personnel
Based on your country of origin and import market, we will assign dedicated sales personnel to ensure personalized service that meets your specific needs.
Confirm purchase quantity and price, sign contract
Once you confirm the products and prices, we will sign a formal contract with you, outlining purchase quantities, prices, and other essential terms to safeguard both parties' interests.
Customized production
According to your order requirements, we offer customization services to ensure products meet your specific needs. We will produce the goods according to your specifications and deliver them promptly.
Brand collaboration for promotion
If you have branding and promotional needs, we provide collaborative services to help establish your brand image in the market and boost product sales.
After-sales service
We pledge to provide high-quality after-sales service, assisting you in resolving any issues that may arise during product usage. Your satisfaction is our utmost priority.
Thank you for choosing our medical supplies. We look forward to establishing a long-term partnership with you. If you have any questions or need further information, please feel free to contact our customer service team. Wishing you a pleasant shopping experience!
Our Certificate

Singderm CE

Singfiller CE

ISO

SMDR
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Singclean Medical is one of the leading hyaluronic acid dermal filler manufacturers and suppliers in China. with many highly qualified staff and advanced technology, we warmly welcome you to wholesale our quality hyaluronic acid dermal filler at competitive price which has no doubt to bring you many benefits.
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