Medical Sodium Hyaluronate Gel
team introduction
Hangzhou Singclean Medical Products Co., Ltd., established in 2002 with registered capital of 80,000,000 RMB, is a national high and new technology enterprise integrating the R&D, production and sales of medical biomaterials. With highly-qualified staff, thorough quality management system and first-class facilities, the company ensures the continuous production of medical devices of Class III that conform to the laws and regulations of NMPA and EU MDR.

Rich Experience
Singclean Medical has been committed to promoting the development of medical sodium hyaluronate industry for over 20 years. In 2011, Singclean got CE certification-Sterile Viscoelastic Solution for Ophthalmic Surgery. In 2012, Singclean got CE certification-Medical Sodium Hyaluronate Gel for Bone Joint. In 2017, Singclean got CE certification-Medical Sodium Hyaluronate Gel for Anti-adhesion.
Quality Certified
Factory with CE, ANVISA, ISO13485, BGMP & MDSAP certification. Production equipment and processes complying with international standards. Obtained local registration in 50+ countries including EU countries, Brazil and other countries.


Strong Factory Strength
28,000 square meters international intelligent manufacturing base. Expansion of 20,000 square meters of complex building. With 900 square meters of cross-linked sodium hyaluronate gel workshop-class 10,000 cleanroom. High cleanliness of the production environment, 10,000-level workshop, local 100-level environment, to ensure the safety of every piece of our product.
Global Supply
Singjoint® medical sodium hyaluronate gel has obtained registration in over 40 countries, including UK, European Union, Malaysia, Paraguay, Venezuela, Egypt, Türkiye and many more. With its expanded reach, Singjoint® is bringing relief to an even larger population of individuals suffering from OA.

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Singjoint medical sodium hyaluronate gel (for bone joint), is non-animal original, with the advantages of high viscoelasticity, lubricity, physical alterability and good biocompatibility. It is a medical polymer extracted and refined by high-tech bio-engineering from streptococcal fermentation metabolites. It is sterile, and free from pyrogenicity, allergy, genetic toxicity, or skin irritation. Due to fermentation production of HA, the product has no risk of being a virus carriers and dissemination medium when extracting animal tissues or organs. This product can be used as an orthopedics agent to improve the joint function. When used for injections in joint cavities, due to its macromolecular characteristic and good viscoelasticity, it stimulates synovium to produce high molecular sodium hyaluronate, which is beneficial for releasing joint pain, increasing mobility, decreasing synovitis and delaying progression of disease.
SingJoint® Injection
10mg/ml 12mg/ml
● EP approved non-animal sourced HA
● Series of 3 or 4 injections
● Ideal Molecular Weight ≥1.0M Daltons
● Through 6 months long-lasting pain relief
● For People who like a series of treatments for financial or other reasons
SingJoint® Plus Injection
● 20mg/ml highly concentrated
● EP approved non-animal sourced HA
● Single injection regimen
● Ideal Molecular Weight ≥ 1.6M Daltons
● Over 6 months long-lasting pain relief
● For People who require faster recovery
The advantages of Singjoint medical sodium hyaluronate gel (for bone joint)
Performance:
In clinical studies, Singjoint® has shown to relieve OA knee pain for 6 months.
Safety:
No adverse events occurred.
No serious adverse events occurred.
Better Patient Compliance: Excellent biocompatibility due to bio-fermentation,
no immunogen, biodegradable.
Effective:
High Concentration of HA, Creating a high viscosity
environment to replicate healthy joint function.
High Molecular Weight
Long lasting pain relief
Delay total knee replacement (TKR) surgery
Convenient:
Administered in doctor’s office
Singclean® (Medical Sodium Hyaluronate Gel) Viscoelastic Solution For Ophthalmic Surgery
Singclean® (medical sodium hyaluronate gel) viscoelastic solution for ophthalmic surgery, being animal-origin free and of high viscoelasticity, lubricity, physical alterability and good biocompatibility. It is medical polymer extracted and refined by high-tech bio-engineering from streptococcal fermentation metabolites. It is sterile, and free from pyrogenicity, allergy, genetic toxicity, or skin irritation. Due to fermentation production, the product is free from the risk of virus carriers and dissemination medium when extracting animal tissues or organs. Singclean is indicated for helping to prevent or reduce postoperative adhesions after abdominal and pelvic surgery.

Sodium hyaluronate OVDs can help achieve excellent chamber maintenance during phacoemulsification and intraocular lens (IOL) insertion and removal due to their higher viscosity and molecular weight
Minimize the interaction between instrument and tissue and absorb shock, protect the corneal endothelium while maintaining exceptional clarity.
High viscosity, promote the separation of adhesions and blood clots
Lubrication, bring out the blood clots and tissue fragments together
Promote wound healing, prevention of contact adhesion.
The advantages of Singclean® (medical sodium hyaluronate gel) viscoelastic solution for ophthalmic surgery
Raw material sodium hyaluronate comes from bacterial fermentation, no pyrogen and rejection reaction, with good biocompatibility, etc.
High cleanliness of the production environment, 10,000-level workshop, local 100-level environment, to ensure the safety of the product.
High transparency of the products. Before leaving the factory, each product is tested by lamp test, eliminating any product containing foreign impurities, providing a good vision for surgery.
Automated operation, using Sweden Inova automated filling machine filling, the product does not contact with people.
High molecular weight of 1,000,000~2,600,000 Daltons, shear viscosity ≥100,000 mPa-s, which is conducive to the stable operation of repeated movement of surgical instruments during the surgical process and the reduction of mechanical damage in ultrasound; surgical instruments during surgery and reduce mechanical damage in ultrasound.
Good cohesion, can well maintain the depth of the anterior chamber.
Pre-filled syringe packaging + blister packaging. It can prevent impact/vibration during transportation from affecting the product's sterility barrier.
How to use Singclean® (medical sodium hyaluronate gel) viscoelastic solution for ophthalmic surgery
First expulse the air out of the ophthalmic luer-lock needle , then inject Singclean® appropriately into eye.
The injected amount must be adapted to the type of surgical procedures.
The administration of Singclean® should be performed only by trained specialists.
Over tightening may cause the hub to weaken and possibly detach from the syringe. Extrusion of a test droplet is recommended prior to entering eye, and excessive force on the plunger should be avoided.

Singclean medical sodium hyaluronate gel for anti-adhesion, being animal-origin free and of high viscoelasticity, lubricity, physical alterability and good biocompatibility. It can form a network of macromolecules on the surface of the tissue, build a biomechanical barrier, block inflammation from normal serosal membranes and prevent tissue adhesion. Its lubricating properties can also reduce friction during wound healing and promote wound healing. As a barrier to prevent adhesion, appropriate degradation time is crucial, and generally more than 7 days of HA will endanger the healing process of peritoneal wounds.
The advantages of Singclean® medical sodium hyaluronate gel for anti-adhesion
Advantage 01
Safe、Optimized absorption time of 7 days
Advantage 02
Produced by bacterial fermentation without the risk of virus carriage.
Advantage 03
Excellent biocompatibility
Advantage 04
It is completely degraded in the body and naturally cleared from the body.
Advantage 05
Hyaluronic acid is a naturally occurring substance found in the human body. This natural biocompatibility means there is no autoimmune rejection and it is less likely to cause adverse reactions.
Advantage 06
Degradation of hyaluronic acid (HA) beyond 7 days will endanger the healing process of peritoneal wounds.
How to use Singclean® medical sodium hyaluronate gel for anti-adhesion?
1. Open Singclean® box and take the product out.
2. Follow the indication, peel-open the blister tray, remove the Singclean® syringe and place on sterile field.
3. After abdominal and pelvic surgery, inject Singclean® gel into the cavity to completely cover the surface of the organs.
4. In order to achieve the best adhesion prevention results, the gel should not only be applied to the organs that are operated on but also to cover organs away from the surgical areas as much as possible.
5. The amount of gel in every single use depends on the area of surgical wounds. The maximum dosage regimen is no more than 50mL.
What Is Osteoarthritis (OA) of the Knee?
OA is a common condition that causes joints to become stiff and painful. It is most common in the elderly.
With OA of the knee, less synovial fluid which contains hyaluronic acid is produced naturally in the knee joint while synovial fluid acts as the knee's shock absorber and protects cartilage coverings from wear and tear. Gradually, as joint fluid continues to break down and cartilage eteriorates, bones may start to rub against each ther, leading to pain, stiffness, swelling and imited joint activity.
Who is at Risk for OA?
People over age 45
Obesity, overweight will put an extra pressure on knees
Gender, OA is more prevalent in women, after age 55
Young people with sports related injuries
Athletes needing viscoelastic supplement for joint lubrication and mechanical support
People with osteoarthritis have already been treated with pain relievers and other treatments did not work well
Mechanisms of different types of Ophthalmic surgery)
A. Cataract surgery and IOL implantation
The required amount of SINGCLEAN is slowly infused through a needle or cannula into the anterior chamber. The protective effect of SINGCLEAN as an aid is optimized when the injection is performed prior to cataract extraction and insertion of the lOL and is effective for both intra- and extra-capsular procedures. SINGCLEAN may be applied to lOL prior to insertion. Additional SINGCLEAN can be injected as required to facilitate surgical procedures.
B. Corneal transplant surgery
The corneal button is removed and the anterior chamber filled with SINGCLEAN is at level with the surface of the corneal. The donor graf is then placed on top of the SINGCLEAN and sutured into place. Additional SINGCLEAN can be used as required to aid in surgical procedures.
C. Glaucoma filtration surgery
SINGCLEAN is injected through a corneal paracentesis to restore and maintain anterior chamber volume during the performance of the trabeculectomy. Additional SINGCLEAN can be used as required to aid in the surgical procedures.
D. Secondary lens implantation
Before removing the IOL, a viscoelastic agent is injected into the anterior chamber to maintain the original depth of the anterior chamber, and the IOL is removed from the anterior chamber.
What is Adhesion?
Adhesion refers to the formation of abnormal connections or bonds between adjacent tissues or organs that are normally separate. It can occur after surgery when the body's natural healing process leads to the deposition of abnormal connective tissue around the surgical site.
This connective tissue, known as fibrous adhesions, can cause the tissues or organs to become stuck together, leading to complications and impairing their normal function.
Although adhesions can occur anywhere, the most common locations are within the:
1,Abdominal cavity: include organs such as the intestines, liver, stomach, or reproductive organs.
2,Pelvic region: involve the uterus, fallopian tubes, ovaries, or other pelvic organs.
3,Tendons and joints
4,Spine and spinal nerves
The incidence of adhesions ranges from 67–93% after general abdominal surgery and can have rates up to 97% after open gynecologic pelvic procedures.
How to cooperate with us
Submit Inquiry
You can send inquiries to us via email or other channels, providing your requirements and relevant information. Our professional team will respond promptly, offering detailed product information and quotations.
Assignment of Sales Personnel
Based on your country of origin and import market, we will assign dedicated sales personnel to ensure personalized service that meets your specific needs
Confirm Purchase Quantity and Price, Sign Contract
Once you confirm the products and prices, we will sign a formal contract with you, outlining purchase quantities, prices, and other essential terms to safeguard both parties' interests
Customized Production
According to your order requirements, we offer customization services to ensure products meet your specific needs. We will produce the goods according to your specifications and deliver them promptly.
Brand Collaboration for Promotion
If you have branding and promotional needs, we provide collaborative services to help establish your brand image in the market and boost product sales
After-Sales Service
We pledge to provide high-quality after-sales service, assisting you in resolving any issues that may arise during product usage. Your satisfaction is our utmost priority
Thank you for choosing our medical supplies. We look forward to establishing a long-term partnership with you. If you have any questions or need further information, please feel free to contact our customer service team. Wishing you a pleasant shopping experience!
Certifications

ISO

CE

CE

ANVISA

ANVISA
Our Factory
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Singclean Medical is one of the leading medical sodium hyaluronate gel manufacturers and suppliers in China. with many highly qualified staff and advanced technology, we warmly welcome you to wholesale our quality medical sodium hyaluronate gel at competitive price which has no doubt to bring you many benefits.
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