Osteoarthritis (OA) is a progressive degenerative joint disease characterized by the gradual breakdown of articular cartilage and deterioration of synovial fluid quality.
Under healthy conditions, synovial fluid acts as a natural lubricant and shock absorber within the knee joint. Hyaluronic acid is the principal component responsible for maintaining the fluid's viscoelastic properties.
As osteoarthritis progresses:
• Synovial fluid becomes diluted and less effective.
• Cartilage surfaces lose protection.
• Bone-on-bone friction increases.
• Pain, stiffness, swelling, and mobility limitations develop.
Singjoint Injectable hyaluronic acid gel has become one of the most widely adopted non-surgical treatment options for knee osteoarthritis worldwide.
SingJoint® Medical Sodium Hyaluronate Gel is a premium viscous HA injection manufactured by Singclean Medical using advanced bacterial fermentation technology. Designed to replace and supplement pathological synovial fluid, it helps restore joint lubrication, reduce pain, and improve mobility in patients suffering from osteoarthritis of the knee.
According to global epidemiological studies, more than 528 million people worldwide are affected by osteoarthritis, making it one of the leading causes of disability among adults aged 45 years and older. The growing aging population, rising obesity rates, and increasing incidence of sports-related joint injuries continue to drive demand for effective viscosupplement injection therapies.
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Microbial fermentation method derived from streptococcus.
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A mucopolysaccharide naturally occurring in nature.
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Animal-free, excellent biocompatibility.
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Intrinsic composition of joint synovial fluid;
Matches healthy synovial fluid;
Viscosupplement injection therapy addresses this biomechanical deficiency by introducing purified hyaluronic acid directly into the joint cavity. Acting as a biological joint filler, the injected hyaluronic acid helps restore lubrication, absorb mechanical stress, and improve joint movement.
For patients with mild to moderate knee OA, viscosupplementation has become an important treatment option between conservative therapies and total knee replacement surgery.
Common candidates include:
• Adults aged 45 years and older
• Overweight or obese individuals
• Patients with previous joint injuries
• Athletes requiring additional joint lubrication
• Patients inadequately relieved by analgesics or corticosteroids
Sodium Hyaluronate Injection - SingJoint® Specifications
| products |
 |
 |
| Hyaluronic Acid Orthopedics Parameters | SingJoint® | SingJoint® Plus |
| Product Type | hyaluronic acid intra articular injection | Advanced hyaluronic acid intra articular injection |
| Source | Bio-fermentation | Bio-fermentation |
| Concentration | 10mg/ml or 12mg/ml | 20mg/ml |
| Molecular Weight | ≥1.0 Million Daltons | ≥1.6 Million Daltons |
| Administration Protocol | 3-4 injections | Single injection |
| Duration of Relief | Up to 6 months | More than 6 months |
| CE Certification | Yes | Yes |
| Clinical Studies | Available | Available |
| Sales Coverage | 90+ Countries | 90+ Countries |
Therapeutic Efficacy
Sodium Hyaluronate Injection for Osteoarthritis
SingJoint® is indicated for the treatment of symptoms associated with knee osteoarthritis.
By replacing and supplementing pathological synovial fluid within the affected joint, the product helps:
• Reduce knee pain
• Improve joint mobility
• Enhance shock absorption
• Support normal biomechanical function
• Delay disease progression
• Potentially postpone total knee replacement procedures
Compared with systemic therapies, localized viscosupplementation offers targeted therapeutic effects while minimizing systemic exposure.
Clinical Efficacy and Key Performance Indicators
For distributors and healthcare procurement teams, objective product performance metrics are essential.
Compared with a leading Turkey-origin competitor, SingJoint® demonstrates substantial advantages across multiple critical parameters.
Higher Concentration
SingJoint® delivers a sodium hyaluronate concentration level approximately 102% higher than comparative products, creating a stronger viscoelastic environment that more closely replicates healthy synovial fluid.
Superior Biocompatibility
SingJoint® osmolality:
313 mOsm/kg
This closely matches physiological human conditions, supporting enhanced patient comfort and improved injection tolerance.
Competitor products:
326–328 mOsm/kg
Quick Purchasing Information
| Item | Details |
|---|---|
| MOQ | Flexible MOQ for distributors and OEM projects |
| Available Specifications | 10 mg/mL, 12 mg/mL, 20 mg/mL (Single & Multi-injection Options) |
| Molecular Weight | ≥1.0 MDa / ≥1.6 MDa (Depending on Model) |
| OEM / ODM | Available |
| Private Label | Supported |
| Shelf Life | 2 Years |
| Lead Time | Stock Orders: 7–15 DaysOEM Orders: 25–35 Days |
| Sterilization | Sterile, Single-use |
| Regulatory Support | CE, MHRA, ANVISA registration support |
| Export Markets | Available in more than 80 countries and regions |
| Samples | Available for distributor evaluation |
Certification
SingJoint® is manufactured according to:
• ISO 13485 Quality Management System
• CE Certified Medical Device Standards
• Brazilian ANVISA Standards
• International Medical Device Manufacturing Requirements
Recommendations From Doctors and Distributors
Global Sales & Safety Record
Manufacturing Excellence and Quality Assurance
For orthopedic distributors and healthcare procurement professionals, manufacturing consistency is just as important as clinical efficacy.
At Singclean Medical, every batch of SingJoint® Medical Sodium Hyaluronate Gel is produced under a comprehensive quality management system certified to ISO 13485 standards and complies with CE regulatory requirements.
Unlike animal-derived hyaluronic acid products, SingJoint® utilizes non-animal sourced hyaluronic acid produced through controlled bacterial fermentation.
Benefits include:
• No animal protein residues
• No immunogenic risks associated with avian sources
• Superior batch-to-batch consistency
• Enhanced purity and safety profile
• Excellent biodegradability and biocompatibility
B2B Partnership - OEM/OBL and Private Label Solutions
As global demand for gel injections for knee osteoarthritis continues to increase, distributors are actively seeking reliable manufacturing partners capable of delivering regulatory compliance, supply stability, and competitive market positioning.
Singclean Medical provides comprehensive OEM, OBL, and private label services for orthopedic product distributors worldwide.
Why Distributors Choose Singclean
Established Manufacturing Expertise
• More than 20 years of medical device manufacturing experience
• Export presence in over 80 countries and regions
• Dedicated orthopedic biomaterials development team
• Mature regulatory documentation support
FAQ
Q1: What is SingJoint® Medical Sodium Hyaluronate Gel used for?
A: SingJoint® is a medical sodium hyaluronate gel indicated for the treatment of symptoms associated with knee osteoarthritis. Acting as a viscosupplement injection and joint filler, it helps restore lubrication, reduce pain, and improve joint mobility.
Q2: How long does the effect of SingJoint® last?
A: Depending on the formulation used and patient condition, SingJoint® may provide pain relief for up to 6 months or longer. SingJoint® Plus is specifically designed to deliver long-lasting efficacy with a single injection regimen.
Q3: What makes SingJoint® different from other orthopedic gel injections?
A: Compared with many competing products, SingJoint® offers:
• Higher HA concentration
• Higher molecular weight
• Better physiological osmolality
• Longer-lasting efficacy
• Excellent biocompatibility through non-animal sourced bio-fermentation technology
Q4: Are intra-articular hyaluronic acid injections safe?
A: When administered by trained healthcare professionals using aseptic techniques, intra-articular hyaluronic acid injections are generally considered safe and well tolerated. Temporary injection-site discomfort or swelling may occasionally occur and typically resolves within a few days.
Q5: Can distributors obtain OEM or private label services?
A: Yes. Singclean Medical offers OEM, OBL, and private label solutions for distributors, importers, hospital suppliers, and orthopedic product brands worldwide.
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