Why Sodium Hyaluronate Is the Preferred Ophthalmic Viscoelastic in Modern Eye Surgery

Jun 04, 2026

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Cataract surgery, glaucoma procedures, corneal transplantation, and intraocular lens implantation all require precise surgical environments where tissue protection and space maintenance are critical. This is why the choice of an ophthalmic viscosurgical device (OVD) has become one of the most important factors influencing surgical outcomes.

 

Among various viscoelastics in ophthalmology, sodium hyaluronate-based ophthalmic viscoelastic devices have emerged as the gold standard for many ophthalmic surgeons worldwide. Their superior biocompatibility, excellent chamber maintenance, and endothelial cell protection have made them the preferred choice over alternative materials such as hydroxypropyl methylcellulose (HPMC).

 

In this article, we explore why sodium hyaluronate continues to dominate the OVD market and how Singclean® OVD delivers reliable performance for distributors, hospitals, and ophthalmic clinics.

 

OVD 10

 

What Is an Ophthalmic Viscoelastic Device?

An ophthalmic viscoelastic device is a sterile polymer solution used during eye surgery to:

Maintain anterior chamber depth

Protect corneal endothelial cells

Separate ocular tissues safely

Facilitate intraocular lens implantation

Reduce mechanical trauma caused by surgical instruments

Without a properly selected ophthalmic viscosurgical device, surgeons may face challenges such as chamber collapse, endothelial cell damage, poor visibility, and increased surgical complexity.

According to the Singclean OVD product portfolio, sodium hyaluronate-based OVDs help maintain chamber stability during phacoemulsification while minimizing tissue trauma and enhancing surgical visibility.

 

Excellent Space Maintenance During Cataract Surgery

Cataract surgery remains the largest application segment for ophthalmic viscoelastic devices globally.

During phacoemulsification, maintaining anterior chamber depth is essential because surgeons need adequate working space while protecting delicate ocular structures.

The effectiveness of sodium hyaluronate largely depends on molecular weight and viscosity.

 

Clinical Comparison: Sodium Hyaluronate vs HPMC

Parameter Typical HPMC OVD Singclean Sodium Hyaluronate OVD
Molecular Weight ~86,000 Da 1,000,000–2,600,000 Da
Viscosity 3,000–5,000 mPa·s ≥100,000 mPa·s
Classification Dispersive Cohesive
Chamber Maintenance Moderate Excellent
Removal Efficiency Moderate Excellent

 

The significantly higher molecular weight and viscosity of sodium hyaluronate provide better chamber stability throughout repeated instrument insertion and manipulation.

For complex cataract surgeries, this stability translates into:

Better surgical control

Reduced endothelial trauma

Improved visibility

Enhanced surgeon confidence

 

Cohesive Properties Simplify Surgical Workflow

OVDs are generally classified into:

Cohesive OVDs

Dispersive OVDs

Viscoadaptive OVDs

Each category has its own advantages, but cohesive OVDs remain popular because they maintain space effectively and can be removed as a single mass after surgery.

Singclean® OVD is classified as a cohesive ophthalmic viscosurgical device. It forms a unified viscoelastic mass that:

Maintains intraocular space

Stabilizes ocular tissues

Simplifies aspiration

Helps minimize postoperative pressure spikes

These characteristics are particularly appreciated by surgeons performing routine cataract procedures.

 

 

Applications of Singclean Ophthalmic Viscoelastic Device

Singclean sodium hyaluronate ophthalmic solution is designed for:

Cataract Surgery

The largest application segment globally, supporting phacoemulsification and IOL implantation.

Corneal Transplantation

Maintains chamber depth and facilitates graft positioning.

Glaucoma Filtration Surgery

Helps restore and maintain anterior chamber volume during trabeculectomy.

Secondary Lens Implantation

Provides space maintenance and tissue protection during lens exchange procedures.

For more detailed product specifications, visit:

OVD for Ophthalmic Surgery:
Singclean Ophthalmic Viscoelastic Device

 

Conclusion

As ophthalmic surgery continues to evolve, surgeons increasingly require ophthalmic viscosurgical devices that combine excellent tissue protection, stable chamber maintenance, ease of removal, and reliable clinical performance.

Sodium hyaluronate remains the preferred material because it delivers the optimal balance of:

Biocompatibility

Viscoelasticity

Endothelial protection

Surgical efficiency

For distributors, hospitals, and ophthalmic clinics seeking a dependable OVD partner, Singclean® offers a compelling combination of clinical performance, manufacturing quality, regulatory readiness, and global market experience.

 

Looking for a Reliable Ophthalmic Viscoelastic Device Supplier?

Partner with Singclean® to access high-quality sodium hyaluronate OVD solutions trusted by ophthalmic professionals worldwide.

Cohesive OVD for cataract and anterior segment surgery
Non-animal bio-fermented sodium hyaluronate
Multiple concentrations and syringe sizes available
CE-compliant manufacturing and global export experience
OEM/Private Label Support for International Distributors

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