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What is Osteoarthritis (OA) of the knee?
Knee joint is lubricated by synovial fluid, which contains hyaluronic acid and acts as the knee's shock absorber and protects cartilage coverings from wear and tear.
With OA of the knee, less synovial fluid is produced naturally in the knee joint. Gradually, as joint fluid continues to break down and cartilage deteriorates, bones may start to rub against each other, leading to pain, stiffness, swelling and limited joint activity.
Hyaluronic Acid is the most important component of synovial fluid, high viscoelasticity, lubricity, physical alterability of HA provide better lubrication and shock absorption.


Effective Solution for Osteoarthritis Treatment -- Singjoint Knee Gel Injections
SingJoint® knee gel injections is indicated for the treatment of symptoms of osteoarthritis of knee. By replacing and supplementing the pathological synovial fluid in the osteoarthritic joints, it reduces pain and improves joint function.

The Pain Points in the Viscosupplementation Market
Short Duration of Relief: Standard products require repeat injections every 3-4 months, increasing patient burden and clinic traffic.
Injection Discomfort: Higher osmolality levels in some generic HA gels can cause post-injection swelling or discomfort.
Limited Differentiation for Distributors: Competing on price alone with low-value generic HA products erodes margins.
Specification
|
Features |
SingJoint® |
SingJoint® Plus |
|
Ingredient |
HA |
HA |
|
Source |
Biofermentation |
Biofermentation |
|
Molecular weight |
≥1.0 Mda |
≥1.6Mda |
|
Concentration |
10mg/ml, 12mg/ml |
20mg/ml |
|
Volume |
1.0ml, 2.0ml, 2.5ml |
2.0ml, 3.0ml |
|
Total HA Concentration |
10mg-30mg |
40mg, 60mg |
|
Type of HA configuration |
Linear |
Linear |
|
Monthly administration |
3 - 4 injection, once a week for 3 to 4 consecutive weeks. |
1 Injection |
|
Duration |
Up to 6 months |
6 months+ |
|
CE |
Yes |
Yes |
|
Safety |
Safe |
Safe |
|
Clinical studies |
Yes |
Yes |
|
Sales coverage |
90+ |
90+ |
Therapeutic Efficacy


Better Patient Compliance:
Excellent biocompatibility due to bio-fermentation, no immunogen, biodegradable.
Effective:
High Concentration of HA: Creating a high viscosity environment to replicate healthy joint function.
High Molecular Weight
Long lasting pain relief
Delay total knee replacement (TKR) surgery
Convenient:
Administered in doctor's office

"Singjoint® has been proven to provide long-lasting relief of OA knee pain." A total of 300 cases of arthrophlogosis subjects were enrolled, the clinical study was performed in First Affiliated Hospital of Zhejiang Chinese Medical University and Tongde
Hospital ofZheiiang Province, two Grade A hospitals in China.
In clinical studies, Singjoint® has shown to relieve OA knee pain for 6 months.
The average effectiveness rate was 99.33% of 20mg/ml product and 99.00% of 10mg/ml product during 6 months.
Safety
No adverse events occurred.
No serious adverse events occurred.
SingJoint® in Clinical Practice: A Trusted Tool for Orthopedic Specialists
SingJoint® is designed for seamless integration into outpatient orthopedic workflows. The procedure is straightforward, minimally invasive, and can be completed in a standard consultation room. Below is a step-by-step overview of the clinical application process, demonstrating the simplicity and safety that physicians and patients appreciate.
Certification



We are proud to hold CE certification, ISO 13485 quality management system certification, and ANVISA approval, ensuring the safety, efficacy, and reliability of our products. These certifications reflect our commitment to delivering high-standard medical solutions and meeting the regulatory requirements of global markets. Partnering with Singclean Medical means choosing a trusted manufacturer with proven quality and compliance.
Recommendations From Doctors and Distributors

Global Sales & Safety Record

Grow Your Orthopedic Business with SingJoint®
Protected Profit Margins: Our competitive ex-factory pricing structure allows for significant value-added distribution margins.
Fast & Flexible OEM Service: Need a private label? We offer custom printing on pouches and boxes with a typical OEM delivery time of just 30 days.
Low MOQ for Trial Orders: Test market demand with minimal inventory risk.
Comprehensive Regulatory Support: We provide full technical documentation (Product Dossier, FSC) to support your local registration process.
Samples Available: Stock samples ready for evaluation within 3-5 working days.

FAQ
Q1: Can I have a sample for our testing?
Q2: What is sample ready time?
Q3: What about the payment methods?
Q4: What's your delivery time?
Q5: Can I print our logo on the package?
Q6: Are you a factory or trading company?
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