PLLA-HA Hybrid Filler: The Regenerative Aesthetic Product That Differentiates Your Portfolio
Today's aesthetic patients are looking for more than temporary wrinkle correction. They increasingly prefer treatments that deliver natural-looking results, longer-lasting outcomes, and collagen regeneration rather than simple volume replacement.
This shift is driving strong demand for next-generation regenerative injectables that combine immediate aesthetic improvement with long-term skin rejuvenation.
Dual-Action Hybrid Filler for Immediate Volume & Long-Term Collagen Regeneration
Singderm® Collanat PLLA HA Filler is an advanced regenerative dermal filler that combines cross-linked sodium hyaluronate gel with poly-L-lactic acid (PLLA) microspheres to deliver both immediate volumization and progressive collagen regeneration.
Key Pain Points: HA market is saturated with thin margins; PLLA alone has slow visible results. Our hybrid solves both.
One-Line Positioning: The only 2-in-1 filler delivering both instant correction and sustained collagen regeneration.
Specifications
| Item | Specification |
|---|---|
| Core Ingredient | 17mg/mL Sodium Hyaluronate (including cross-linked sodium hyaluronate and non-cross-linked sodium hyaluronate) 16% PLLA microsphere 0.3% Lidocaine |
| Specification | 0.5 mL, 0.75 mL, 1.0 mL, 2×0.75 mL, 2×1.0 mL; supplied with 27G injection needles 1.5 mL, 2.0 mL; supplied with 26G injection needles. |
| Indications | Intended for deep dermis, superficial and deep subcutaneous layers injecting and filling to correct moderate and severe wrinkles. |
| Injection Layer | Deep dermis, superficial and deep subcutaneous layers. |
| Sterility | Sterile |
| Efficacy | Instant fill and long-asting collagen stimulation |
| Suitable For | Mid-face volume reconstruction (such as cheeks and temples), lower face lifting (such as jawline), for those who pursue natural and gradual effects |
| Expected effect time | 2 Years |
Mode of Action - Dual Mode
| Stage | 0-12 Months | 12-24 Months |
| HA Mechanism | Physical Filling, immediate Sculpting → Gradual Degradation, transitioning to Collagen Regeneration Phase | Fully metabolized |
| PLLA Mechanism | Immune Activation → Stimulates Collagen Synthesis (Type I, Type III) |
PLLA microparticles gradually degrade, stimulating fibroblasts to regenerate and continue to work → Stable effect |
| Effects | Immediate Sculpting + Skin Texture Improvement |
Natural firmness + Long-term lifting |
Ready-to-Use Convenience
Unlike other PLLA+HA filler, such as Revexxxx, Etrebxxxx, and other vial-based products, Singderm® Collanat comes in a ready-to-use, pre-filled syringe – not a lyophilized powder in a vial, this fundamental difference bringing significant clinical and practical advantages for practitioners and clinics:
No Reconstitution – Ready to Inject Immediately
Eliminates the Risk of Inconsistent Suspension
Simplified Workflow – Higher Clinic Efficiency
Comfortable Treatment Experience
Built-in lidocaine minimizes discomfort for a smoother and more pleasant experience.
Natural-Looking & Long-Lasting Results
Milky-white gel reduces light refraction, ensuring natural-looking rejuvenation.
Clinical Data
Comparative Advantages of Singderm® Collanat:
Higher Viscosity: Strong resistance to migration, minimal diffusion after injection, ensuring precise shaping.
Higher Elasticity: ldeal for deep-ayer implantation, providing superior structural support and contouring capabilities.
Higher Cross-Linked HA Content: Enhanced mechanical strength, delivering better shaping results and longer durability.
Temples
Eyebrow arch
Nose
Cheeks
Nose base
Jawline
Chin
Before and After
Injection Area: Nose Base, Cheek
Injection Area: Jawline, Cheek
3 Reasons to Partner with Us
•Higher Profit Margins: Regenerative products command premium pricing – far more profitable than commoditized HA fillers.
•Unique Product Differentiation: Few HA+PLLA hybrids on the market – a true competitive edge.
•Flexible Supply Chain: OEM/ODM branding available. Low MOQ options and stable delivery within 30 days.
FAQ
Q: What is a PLLA HA filler?
A: A PLLA HA filler is a hybrid injectable that combines hyaluronic acid for immediate volume correction with poly-L-lactic acid to stimulate collagen production over time.
Q: How long does Singderm® Collanat last?
A: Treatment results can last up to 18 months, depending on the patient's metabolism, injection area, and treatment protocol.
Q: Is Collanat different from traditional HA fillers?
A: Yes. Traditional HA fillers mainly provide temporary volume, while Collanat combines instant correction with long-term collagen regeneration.
Q: Who is suitable for this product?
A: It is intended for qualified medical professionals performing facial rejuvenation and contouring procedures.
Q: Does Singclean provide OEM services?
A: Yes. Singclean supports OEM, private labeling, and global distributor cooperation. We begin by analyzing your target and requirements, works closely with you to understand your design requirement and clarify all product requirements to ensure alignment before development.
Looking for a Premium PLLA HA Filler Supplier?
Expand your aesthetic portfolio with Singderm® Collanat-a next-generation hybrid filler combining instant HA correction with long-lasting PLLA collagen stimulation.
OEM / Private Label Available
Global Distributor Recruitment
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