Stay Ahead of the Next Wave of Aesthetic Medicine
Today's aesthetic patients are looking for more than temporary wrinkle correction. They increasingly prefer treatments that deliver natural-looking results, longer-lasting outcomes, and collagen regeneration rather than simple volume replacement.
This shift is driving strong demand for next-generation regenerative injectables that combine immediate aesthetic improvement with long-term skin rejuvenation.


Dual-Action Hybrid Filler for Immediate Volume & Long-Term Collagen Regeneration
Singderm® Collanat PLLA HA Filler is an advanced regenerative dermal filler that combines cross-linked sodium hyaluronate gel with poly-L-lactic acid (PLLA) microspheres to deliver both immediate volumization and progressive collagen regeneration.
Dual-action Mechanism of Singderm
Unlike conventional hyaluronic acid fillers that mainly restore volume, Collanat is designed with a dual-action mechanism. The HA gel provides instant lifting and contouring immediately after injection, while PLLA microspheres gradually stimulate fibroblasts to promote the body's natural collagen production over time.
This unique hybrid technology helps maintain natural-looking facial volume, improve skin quality, and prolong aesthetic outcomes, making it an ideal solution for patients seeking long-lasting facial rejuvenation.
Designed for professional aesthetic practitioners, Singderm® Collanat is suitable for facial contouring, wrinkle correction, and age-related volume restoration while offering smooth integration into surrounding tissues and natural treatment results.

Dual Benefits in One Injection
Traditional HA fillers mainly deliver instant correction.
Biostimulators mainly focus on collagen regeneration.
Singderm® Collanat combines both advantages into a single injectable solution.
Immediate lifting effect
Long-term collagen remodeling
Natural facial rejuvenation
Extended treatment longevity
High patient satisfaction
Hybrid PLLA + HA Technology
Combines cross-linked hyaluronic acid with PLLA microspheres to achieve immediate filling and long-term tissue regeneration.
Dual-Mode Rejuvenation
Provides instant volume restoration while stimulating endogenous collagen synthesis over time.
Long-Lasting Results
Designed to maintain aesthetic improvements for up to 24 months, reducing treatment frequency compared with conventional HA fillers.
Natural Facial Contours
Gradually restores facial volume while maintaining soft and natural facial expressions.

Specifications
| Item | Specification |
|---|---|
| Core Ingredient | 17mg/mL Sodium Hyaluronate (including cross-linked sodium hyaluronate and non-cross-linked sodium hyaluronate) 16% PLLA microsphere 0.3% Lidocaine |
| Specification | 0.5 mL, 0.75 mL, 1.0 mL, 2×0.75 mL, 2×1.0 mL; supplied with 27G injection needles 1.5 mL, 2.0 mL; supplied with 26G injection needles. |
| Indications | Intended for deep dermis, superficial and deep subcutaneous layers injecting and filling to correct moderate and severe wrinkles. |
| Injection Layer | Deep dermis, superficial and deep subcutaneous layers. |
| Sterility | Sterile |
| Efficacy | Instant fill and long-asting collagen stimulation |
| Suitable For | Mid-face volume reconstruction (such as cheeks and temples), lower face lifting (such as jawline), for those who pursue natural and gradual effects |
| Expected effect time | 2 Years |
Temples
Eyebrow arch
Nose
Cheeks
Nose base
Jawline
Chin

Singderm® vs Traditional HA Fillers
| Feature | Singderm Collanat | Traditional HA Filler |
| Immediate Filling |
|
✔ |
| Collagen Stimulation | ✔ | × |
| Long-Term Regeneration | ✔ | × |
| Hybrid Technology | ✔ | × |
| Natural Volume Restoration | Excellent | Good |
| Treatment Duration | Up to 24 Months | Usually 6–12 Months |
Why Choose Singderm Brand?

Comparative Advantages of Singderm® Collanat:
Higher Viscosity: Strong resistance to migration, minimal diffusion after injection, ensuring precise shaping.
Higher Elasticity: ldeal for deep-ayer implantation, providing superior structural support and contouring capabilities.
Higher Cross-Linked HA Content: Enhanced mechanical strength, delivering better shaping results and longer durability.

Looking for a Premium PLLA HA Filler Supplier?
Expand your aesthetic portfolio with Singderm® Collanat-a next-generation hybrid filler combining instant HA correction with long-lasting PLLA collagen stimulation.
OEM / Private Label Available
Global Distributor Recruitment
FAQ
Q: What is a PLLA HA filler?
A: A PLLA HA filler is a hybrid injectable that combines hyaluronic acid for immediate volume correction with poly-L-lactic acid to stimulate collagen production over time.
Q: How long does Singderm® Collanat last?
A: Treatment results can last up to 18 months, depending on the patient's metabolism, injection area, and treatment protocol.
Q: Is Collanat different from traditional HA fillers?
A: Yes. Traditional HA fillers mainly provide temporary volume, while Collanat combines instant correction with long-term collagen regeneration.
Q: Who is suitable for this product?
A: It is intended for qualified medical professionals performing facial rejuvenation and contouring procedures.
Q: Does Singclean provide OEM services?
A: Yes. Singclean supports OEM, private labeling, and global distributor cooperation.
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