In the realm of orthopedic medicine, advancements in material science have led to remarkable innovations. Among these, microbial fermentation origin hyaluronic acid has emerged as a game-changer. This naturally occurring biopolymer offers a non-animal-derived, pure, and stable solution, revolutionizing orthopedic treatments. This work explores the potential and impact of microbial fermentation origin hyaluronic acid.
About hyaluronic acid
Hyaluronic acid (HA) is a naturally occurring biopolymer present in the human body, mainly found in tissues such as the skin, eyes, joints, and cartilage. It plays a crucial role in maintaining tissue hydration and lubrication. Hyaluronic acid gel is a form of HA that is injected or implanted as a gel and is widely used in both cosmetic and medical fields.
In the orthopedic field, hyaluronic acid gel is primarily used in treatment of joint diseases. When joint cartilage is damaged, friction between the joints increases, leading to pain and restricted movement. Hyaluronic acid gel can create a lubricating film within the joint cavity, reducing friction, alleviating pain, improving joint function, and enhancing the patient's quality of life.
The origin of hyaluronic acid
However, there are difference in the resources of hyaluronic acid, the materials of hyaluronic acid gel for orthopedic surgery. Generally speaking, there are animal origin hyaluronic acid and microbial fermentation origin hyaluronic acid.
Animal-origin hyaluronic acid:
Some hyaluronic acid gel products are extracted from animal tissues. Common animal sources for hyaluronic acid gel include rooster combs, chicken skin, chicken sternum, bovine eyeballs, and other animal tissues. These animal-derived hyaluronic acid gels undergo rigorous biocompatibility processing to ensure their safety and stability.
Microbial fermentation origin hyaluronic acid:
There are also hyaluronic acid gel products that are obtained through microbial fermentation and do not involve animal sources.
The advantages of microbial fermentation origin hyaluronic acid.
Compared to animal origin hyaluronic acid, microbial fermentation origin hyaluronic acid has several advantages:
High purity: The production process of microbial fermentation origin hyaluronic acid is more controllable, resulting in a higher purity product. In contrast, animal origin hyaluronic acid may contain other biological molecules, leading to lower purity.
Sustainable production: Microbial fermentation origin hyaluronic acid is not dependent on animal sources and is produced through bio-synthesis, allowing for sustainable production and avoiding reliance on animal resources.
No risk of animal-borne infections: The production process of microbial fermentation-derived hyaluronic acid does not involve animal tissues, eliminating the risk of animal-transmitted diseases and avoiding potential health and ethical concerns related to animals.
Better stability: Due to its controllable production process, microbial fermentation orgin hyaluronic acid exhibits better stability, maintaining its functionality and performance during storage and use.
The microbial fermentation origin hyaluronic acid in orthopedic surgery fields
Hyaluronic acid (HA) gel, derived through microbial fermentation, has become a valuable tool in orthopedic surgeries. As a non-animal-derived product, it offers numerous benefits in various procedures, particularly in knee joint surgeries and fracture repairs.
A. Knee Joint Surgery: Application of HA Gel Injection
Pain Relief: HA gel injection has proven to be an effective method of alleviating pain for patients suffering from arthritis. Osteoarthritis, for instance, is a common condition that leads to joint pain and stiffness. By injecting HA gel into the affected knee joint, the gel acts as a cushion, reducing friction between the bones, and relieving pain symptoms.
Joint Lubrication: Another essential aspect of HA gel injection is its ability to improve joint lubrication. As osteoarthritis progresses, the natural synovial fluid in the knee joint diminishes, leading to decreased joint lubrication and limited smooth movements. HA gel injection supplements the synovial fluid, enhancing joint lubrication, and ensuring more fluid movements.
B. Fracture Repair: Application of HA Gel Filling
Structural Support: HA gel's filling application plays a crucial role in fracture repair. When a bone fractures, it can lose stability and alignment, potentially leading to delayed healing or complications. HA gel, when carefully injected into the fractured area, provides additional support and stability to the bone, aiding in its proper alignment and healing.
Facilitating Healing: In addition to offering structural support, HA gel creates a favorable microenvironment for bone healing. Its ability to attract water molecules enhances hydration at the fracture site, promoting cell growth, and stimulating bone regeneration. As a result, the bone healing process is accelerated, leading to faster and more efficient recovery.
Non-animal-derived HA gel has revolutionized the field of orthopedic surgery by providing a safe, effective, and versatile alternative. It not only helps in reducing pain and improving joint lubrication in knee surgeries but also serves as a reliable means to support bone fractures and expedite the healing process.
Introduction of Singjoint® Medical Sodium Hyaluronate Gel
Singjoint® Medical Sodium Hyaluronate, being animal-origin free and of high viscoelasticity, lubricity, physical alterability and good biocompatibility, it is medical polymer extracted and refined by high-tech bio-engineering from streptococcal fermentation metabolites. It is sterile, and free from pyrogenicity, allergy, genetic toxicity, or skin irritation.
Singjoint® is indicated for the treatment of symptoms of osteoarthritis of knee. By replacing and supplementing the pathological synovial fluid in the osteoarthritic joints, it reduces pain and improves joint function.
We got CE2460, CFDA, SGS, ISO13485 and ISO9001 certification for the products. For more details, please check the link below.
Singjoint® Medical Sodium Hyaluronate Gel
https://www.singclean.org/medical-sodium-hyaluronate-gel/viscosupplement-injection-for-orthopedics/shots-for-knee.html
Conclusion
As medical technology continues to advance, microbial fermentation origin hyaluronic acid gel is expected to play an increasingly vital role in orthopedic procedures, benefiting patients worldwide. And it has many advantages that animal origin hyaluronic acid gel doesn’t have. For sure microbial fermentation origin hyaluronic acid will gradually play an important role in orthopedic surgery.