Viscosupplement Injections vs Traditional Knee Pain Therapies: Which is More Effective?

Oct 31, 2025

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Understanding Knee Osteoarthritis and Pain Management

Osteoarthritis is a chronic, progressive condition that affects millions worldwide, especially those over 45. As the cartilage in the knee deteriorates, the joint loses its natural cushioning and lubrication, leading to stiffness, swelling, and persistent pain. Managing this condition effectively is crucial to maintaining mobility and quality of life.

Traditionally, treatments for OA have included oral pain medications, corticosteroid injections, and physical therapy. However, these methods often provide only short-term relief or come with side effects. In recent years, viscosupplement injections have emerged as a promising alternative for longer-lasting and safer pain management.

 

What Are Viscosupplement Injections?

Viscosupplement injections involve introducing hyaluronic acid - a naturally occurring substance in joint fluid - directly into the knee joint. The purpose is to restore the viscoelasticity of the synovial fluid, allowing smoother movement and better shock absorption.

Hyaluronic acid plays a vital role in joint lubrication. As OA progresses, the concentration and molecular weight of HA in the synovial fluid decrease, resulting in reduced lubrication and increased friction. By replenishing HA, viscosupplementation helps restore joint function and reduce pain without systemic side effects.

 

How Viscosupplements Compare to Traditional Therapies

Treatment Type

Mechanism of Action

Effect Duration

Drawbacks

Painkillers (NSAIDs, Analgesics)

Reduce inflammation and pain

Short-term (hours to days)

Gastrointestinal issues, dependency risk

Corticosteroid Injections

Decrease inflammation

Weeks to 2 months

May damage cartilage with repeated use

Physical Therapy

Strengthens muscles, improves flexibility

Ongoing benefit with continuous exercise

Time-consuming, may not relieve severe pain

Viscosupplement Injections (HA)

Restore joint lubrication and shock absorption

6 months or more

Mild local discomfort after injection

Compared to these approaches, viscosupplementation offers a unique balance between safety, comfort, and efficacy. It directly addresses the underlying issue-loss of joint lubrication-rather than masking pain symptoms.

 

Singjoint Shots For Knee

 

The Advantages of SingJoint® Viscosupplementation

SingJoint®, developed by Hangzhou Singclean Medical Products Co., Ltd., represents a next-generation viscosupplementation solution designed for patients suffering from mild to moderate osteoarthritis.

Key benefits include:

  • Higher Concentration and Viscosity: SingJoint® contains medical-grade sodium hyaluronate with an ideal molecular weight (≥1.0M–1.6M Daltons), creating a highly viscous environment that closely mimics healthy synovial fluid.
  • Enhanced Biocompatibility: Derived from non-animal, bio-fermented HA, SingJoint® ensures superior compatibility and minimal immune reaction. Its osmolality (313 mOsm/kg) closely matches that of human body fluids, minimizing discomfort.
  • Long-Lasting Relief: Clinical use shows pain relief lasting over six months, significantly longer than traditional therapies like corticosteroids or NSAIDs.
  • Joint Protection and Regeneration: HA injections can stimulate the body's own synovial cells to produce natural HA, slowing down cartilage degradation and improving long-term joint health.
  • Convenient Administration:Typically performed in a physician's office, SingJoint® is available in both single-injection and multi-injection regimens, suitable for different patient preferences.

 

Clinical and Market Outlook

As the global population ages and arthritis rates rise, the demand for safe, effective OA therapies continues to grow. According to industry analysis, viscosupplementation markets are expanding rapidly in Asia-Pacific, North America, and Europe, driven by increasing awareness of minimally invasive treatment options.

With its strong R&D foundation and international certifications, Singclean Medical has become a leading provider of hyaluronic acid-based solutions for orthopedic, ophthalmic, and aesthetic applications. The company's focus on innovation and patient comfort positions SingJoint® as a trusted name in joint pain management.

 

Conclusion

When comparing viscosupplement injections to traditional knee pain therapies, the evidence is clear: viscosupplementation provides longer-lasting relief, fewer side effects, and improved joint mobility.

For patients seeking a treatment that addresses the root cause of pain rather than merely masking it, SingJoint® from Singclean Medical offers an effective and biocompatible solution that supports lasting joint health and mobility.

 

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About Singclean Medical

Hangzhou Singclean Medical Products Co., Ltd. specializes in orthopedic, ophthalmic and aesthetic medical devices. With decades of experience and adherence to European Pharmacopoeia standards, Singclean is dedicated to providing safe, innovative, and effective HA-based solutions for better patient outcomes worldwide.