Last time, in our article The functions of HCG (Part. 1), we introduced the 3 functions of HCG. Nevertheless, HCG is much more complicated than we thought and the functions of HCG is hard to be mentioned all in just one article. Today, we are going to introduce the functions of HCG that we didn’t introduce last time.
4, Transfer of embryo
Just like normal pregnancy, Prog and HCG values should be maintained at corresponding levels with the increase of gestational age after embryo transfer.
Serum HCG levels have a certain predictive value for pregnancy outcome at various time periods in the initial stage of transplantation (most studies focus on 9-21 days), and can guide the next step of treatment in a timely manner clinically, and assist in the early diagnosis of abnormal pregnancy and pregnancy. Manage and follow up patients with high-risk pregnancies.
5, Biochemical pregnancy
Biochemical pregnancy refers to the failure of implantation of fertilized egg, which starts about a week after the formation of the fertilized egg and includes three processes of positioning, attachment and implantation. Problems in any of these processes can lead to biochemical pregnancy, which is essentially a kind of early abortion. Only the elevation of HCG can be detected in the blood, but B-ultrasound examination cannot show the formation of the gestational sac.
The causes of biochemical pregnancy have not been fully understood, and are related to both fetal and maternal factors. Among them, uterine tolerance, maternal hormone secretion and fetal quality are closely related to biochemical pregnancy.
The diagnosis of early abortion in clinic mainly relies on B-ultrasound, which has a significant effect, but it is difficult to detect biochemical pregnancy. However, Prog combined with HCG detection can better diagnose biochemical pregnancy, which is conducive to the early diagnosis of patients, and has the advantages of high accuracy, high specificity and sensitivity, which is worthy of clinical promotion and application.
6, Residual fetal matter after abortion
After induced abortion, HCG should decrease sharply until normal. If low levels of HCG are still detected after a period of time, it may be due to residual fetal matter from an incomplete abortion.
7, Early spontaneous abortion
The incidence of spontaneous abortion is about 10-15%, most of the spontaneous abortion occurs in the early pregnancy, the cause is complex, there are placental factors, there are maternal factors.
In this case, it may be due to placental dysplasia, or may be caused by insufficient maternal secretion of Prog. Low Prog and HCG values may also lead to biochemical pregnancy, which should be combined with other tests.