Cause of postoperative abdominal (pelvic) cavity adhesion

Jan 30, 2023

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What is abdominal pelvic tissue adhesion?

The formation of adhesions is a kind of inflammatory reaction of fibroplasia. The factors that cause adhesion are complex, which are partial related to the formation of rough surface of abdominal organs, ischemic injury, local inflammatory response, immunohypia, immunohyperplasia or immunodeficiency, etc.

 

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Mechanical or chemical stimulation of the intestinal canal during abdominal surgery, including surgical operation, ischemia, long-term exposure and dry stimulation of the intestinal canal, abdominal blood, pus, exudate and foreign body stimulation, can cause serous membrane injury and lead to inflammatory response, destroy the balance between the release of fibrinogen and fibrinolysis in peritoneal mesothelium cells, and cause fibroblast proliferation. Caused by increased secretion of collagen fibers.

 

Ischemia results in the growth of new capillaries, which form fibrous adhesion after institutionalization, and then cause visual obstruction in the gastrointestinal tract and other related parts.

 

At present, there are two main reasons for abdominal adhesion: peritoneum is stimulated and damaged by various factors. Peritoneal inflammation or injury of peritoneal fibrin exudation: such as reduced fibrinolytic activity, fibrin deposition mechanical persistent adhesion; If the fibrinolytic activity is normal, the fibrinolytic part of the adhesion is not adhesion.

 

Adhesive ileus is intestinal obstruction caused by intestinal adhesion or intraperitoneal adhesion, which is relatively common, and its incidence rate accounts for 20%~40% of all kinds of ileus. Adhesive ileus is the extensive intestinal adhesion formed after abdominal surgery, inflammation and trauma. Acute intestinal obstruction caused by adhesive bands is the most common type of ileus.

 

Singclean medical sodium hyaluronate gel for anti-adhesion is composed of repeating disaccharide units of glucuronic acid and N-acetylglucosamine, its chemical formula is (C14H21NO11)n. It is used for the prevention and reduction of postoperative adhesions of the abdominal and pelvic surgery. It's safe, natural and absorbable, so it will leave no side effects to our bodies. It's quick and easy application to prevent or reduce adhesion formation. Due to the animal origin free, it’s good biocompatibility to our bodies.

An Anti-adhesion Gel