What Is Osteoarthritis and Why Synovial Fluid Matters
Osteoarthritis (OA) is one of the most common degenerative joint diseases, affecting millions of people worldwide-particularly those over the age of 45. The condition is characterized by the gradual breakdown of articular cartilage and the loss of natural joint lubrication.
In a healthy knee, synovial fluid acts as a lubricant and shock absorber, maintaining smooth movement and protecting cartilage surfaces. However, in OA patients, the viscosity and elasticity of synovial fluid decrease, leading to increased friction, stiffness, and pain.
What Are Artificial Synovial Fluid Injections?
Artificial synovial fluid injections-also known as viscosupplementation-involve the injection of hyaluronic acid (HA) into the knee joint. HA is a natural mucopolysaccharide and a major component of healthy synovial fluid. These injections restore the viscoelastic properties of the fluid, reducing pain and improving joint function.
Hyaluronic acid works by:
- Enhancing joint lubrication and shock absorption
- Supporting cartilage regeneration
- Reducing inflammation and oxidative stress
- Stimulating the body's natural HA production
This therapy is especially recommended for mild to moderate osteoarthritis, providing a non-surgical option to relieve pain and delay the need for knee replacement.
How Artificial Synovial Fluid Injections Work
Once injected into the joint cavity, exogenous HA mimics natural synovial fluid. Its viscoelasticity cushions joint surfaces during movement and redistributes mechanical stress.
Moreover, HA interacts with synovial fibroblasts and chondrocytes, stimulating endogenous HA synthesis and protecting cartilage from further degeneration. Clinical studies have shown that HA injections can offer pain relief lasting up to six months, with minimal side effects and excellent patient tolerance.
Introducing SingJoint® – Singclean's Solution for Osteoarthritis Relief
SingJoint® Medical Sodium Hyaluronate Gel by Singclean Medical represents the next generation of artificial synovial fluid injections.
Manufactured through non-animal sourced, bio-fermentation technology, SingJoint® provides a safe and biocompatible viscosupplement designed for reliable pain relief and improved mobility.
Key advantages of SingJoint® include:
- High concentration of HA (10–20mg/ml): Ensures optimal lubrication and cushioning
- Ideal molecular weight (≥1.0M–1.6M Daltons): Balances durability and fluidity for sustained effects
- Long-lasting performance: Up to 6 months of pain relief with either a single or series regimen
- Excellent biocompatibility: Osmolality of ~313 mOsm/kg closely matches human physiology, minimizing injection discomfort
- Convenience: Simple in-office administration by physicians
By replicating the properties of natural joint fluid, SingJoint® restores smooth motion, delays joint replacement, and enhances quality of life for OA patients.
Global Outlook of Viscosupplementation
The global viscosupplementation market is rapidly expanding due to the rising prevalence of osteoarthritis and the aging population. Asia-Pacific and North America currently hold significant market shares, while Europe shows the fastest growth rate due to increasing investments in advanced OA therapies.
As clinicians and distributors seek reliable, long-term solutions, Singclean's SingJoint® stands out for its scientifically engineered formulation, consistent quality, and proven therapeutic performance.
About Singclean Medical
Hangzhou Singclean Medical Products Co., Ltd. is a leading medical device manufacturer specializing in hyaluronic acid-based biomaterials, with products widely used in orthopedics, aesthetics, ophthalmology, and wound care.
For over a decade, Singclean has focused on innovation, safety, and patient comfort-developing products that meet European Pharmacopoeia standards and are trusted by healthcare professionals in more than 80 countries.
By combining advanced biotechnology with strict quality control, Singclean delivers solutions like SingJoint® that improve lives through science-backed, biocompatible medical innovations.