Absorbable Adhesion Barrier Gel
Singclean® is a patented, absorbable sodium hyaluronate gel specifically designed to prevent or reduce postoperative adhesions after abdominal and pelvic surgery.
Prevention or reduction of postoperative adhesions
Abdominal surgery
Pelvic and gynecological surgery
Adult patients undergoing abdominal or pelvic procedures
(excluding pediatric, pregnant, or lactating patients)
What Is Postoperative Adhesion?
Postoperative adhesion refers to abnormal fibrous connections formed between tissues or organs following surgery. During the healing process, inflammation, fibrin deposition, and impaired fibrinolysis can lead to tissues adhering to each other, potentially resulting in chronic pain, infertility, or life-threatening complications such as small bowel obstruction (SBO).
Clinical data show that:
Adhesions occur in 67–93% of patients after general abdominal surgery.
Incidence can reach up to 97% following open gynecologic pelvic procedures.
65–75% of small bowel obstruction cases are caused by adhesion-related disease.
Adhesions begin forming within hours after surgery, making early and effective intervention critical.
Why Use a Physical Anti-Adhesion Barrier?
Current anti-adhesion strategies include:
Surgical technique optimization (limited but not sufficient alone)
Pharmacological intervention (short action time, systemic side effects)
Physical separation barriers (most effective and targeted approach)
Among physical barriers, hyaluronic acid gel offers superior coverage, biocompatibility, and adaptability-especially in minimally invasive surgery.
Mechanism of Action
1. Biomechanical Barrier Formation
Singclean® HA gel forms a three-dimensional macromolecular network on tissue surfaces, physically separating organs and blocking inflammatory infiltration.
2. Optimal Lubrication
The gel reduces mechanical friction between healing tissues, minimizing secondary injury and promoting smoother tissue recovery.
3. Optimized Absorption Time (≈7 Days)
Adhesion formation typically completes within 7 days post-surgery. Singclean® degrades in sync with this period, ensuring:
Continuous coverage during adhesion formation
No interference with long-term peritoneal healing
Clinical Evidence & Safety Profile
Clinical studies involving 307 patients across obstetrics, gynecology, and general surgery
Demonstrated significant reduction in:
Incidence of intrauterine adhesions (IUA)
Moderate and severe adhesion formation
Low incidence of adverse events
Produced via bacterial fermentation, eliminating viral transmission risk
Completely metabolized and naturally excreted
Key Advantages of Singclean Absorbable Adhesion Barrier Gel
High-molecular-weight HA for stable barrier formation
Complete biodegradation with no residue
Excellent tissue adherence and cavity diffusion
Suitable for open and minimally invasive surgery
Proven safety and clinical efficacy
Registered and used in 37+ countries worldwide
Specifications
| Concentration | 10 mg/mL | |||||||||
| Available Volumes | 0.5 mL |
0.75mL |
1.0 mL | 2.0 mL | 2.5 mL | 3.0 mL | 5.0 mL | 15 mL | 17 mL | 20 mL |
Our Certificate
ISO
CE
Contact Us
Looking for a reliable anti-adhesion solution for surgical applications?
Contact us today to request technical documentation, clinical data, or distributor cooperation.
Partner with Singclean® for a proven, globally trusted Absorbable Adhesion Barrier Gel.
FAQ
Q: Are you a manufacturer?
A: Yes, We manufacture products in our factory located in Hangzhou.
Q: What's your main markets?
A: Europe, Asia, Central and South America, MENA, etc.
Q: What is your delivery term?
A: We accept FOB, CIF, etc. You can choose the one which is the most convenient or cost effective for you.
Q: What is the payment term?
A: We receive T/T, Western Union, Paypal, etc.
Q: Will you supply samples for test the quality?
A: We can send you paid or free samples for test , but the clients pay the express charge.
For more information about Absorbable Adhesion Barrier Gel, please feel free to contact marketing@hzxhe.com
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