Medical-grade Collagen Introduction
Collagen exists in many tissues and organs of the
human body. It is produced by fibroblasts and is a
major component of skin, blood vessels, organs,
tendons, ligaments, bones, cartilage and other
connective tissues, as well as the extracellular
matrix of tissue cells. It is an important component
of many tissues in mammals and humans.
Active collagen can be extracted from healthy animal
tissues using specialized separation and purification
techniques.
Medical-grade Collagen has a structure extremely
similar to human collagen, making it an ideal carrier
for human cells. Similar to the extracellular matrix,
it exhibits excellent biocompatibility with living cells.
Utilizing internationally advanced enzymatic digestion technology, the antigen ends are removed, ensuring clinical safety while guaranteeing its tissue reconstruction efficacy after implantation.
Collagen Scaffold Introduction
To increase the tensile strength and biodegradation cycle of
collagen, cross-linking technology can be used to weave
collagen molecules into a stable, porous network structure,
i.e., a collagen scaffold.
As a scaffold, collagen facilitates the migration and proliferation
of cells attached to it, enabling tissue repair and growth in
a predetermined manner, ultimately transforming into the
desired human tissue.
1. Excellent tissue compatibility, preventing rejection.
2. High biodegradability, causing no irritation to the wound.
3. Strong cell growth promotion, facilitating tissue repair.
4. Sufficient mechanical and biomechanical properties, effectively supporting the space maintenance.
Surgiclean®, Medical-grade Active Collagen
Surgiclean® is a sponge-like implantable material composed of active collagen scaffolds, used for safe postoperative wound management and tissue function reconstruction.
Surgiclean® extracts typeⅠcollagen from bovine Achilles tendon, which is extremely similar in structure to human typeⅠcollagen. It is produced according to international ASTM standard processes and uses low-temperature freeze-drying technology to preserve the complete triple helix structure of natural collagen and has safe bioactivity.
Sheet-shaped
The sheet-shaped Surgiclean® has a wide range of applications in dental implants, maxillary sinus lifts, and periodontal surgery.
Plug-shaped
The plug-shaped material can be used to fill tooth extraction sockets, which can significantly accelerate the functional reconstruction of the extraction socket tissue. The plug-shape is
more conducive to clinical operation.
Spatial Structure
Surgiclean®'s unique spatial configuration can rapidly guide cell growth and migration, which is beneficial for tissue regeneration and the fusion of new tissue with the collagen material.
Degradation Cycle
After being implanted into the wound, Surgiclean® gradually degrades and is
absorbed, with a degradation period of 2-4 weeks. It is used for filling extraction
sockets, periodontal and soft tissue surgeries, with a degradation period of
2-3 weeks. For maxillary sinus lifts, the degradation period is 3-4 weeks.
Functions
Safety
Application
| After Tooth Extraction | Alleviates pain | Accelerates healing of soft tissue and bone | Seals the wound, preventing infection and dry socket | |
| Implant Dentistry | Repairs deficient soft tissue | Replaces free gingival grafts | Connective tissue grafts | Reduces tension in GBR procedures |
| Sinus Floor Elevation | Repairs damaged maxillary sinus membrane | Protects the maxillary sinus membrane and helps prevent re-perforation | Can be used in combination with collagen membranes and bone graft materials for a cost-effective solution. | |
| Periodontal Surgery | Protects wound | Reduces inflammation | Improves gingival fullness |
| Specifications (mm) | |||
| Sheet-type | Plug-type | ||
| Rectangular | Square | Truncated Cone | Cylindrical |
| 50×25×2 | 25×25×2 | Φ 7-12x15 | Φ 10×25, Φ 10×20 |
| Φ 5-8x15 | Φ 10×15, Φ 7×15 | ||
Instructions for Use & Precautions
1. Before using the material, the wound must be thoroughly debrided.
2. Collagen has strong adhesion to moist surfaces; keep forceps, gloves, and gauze dry during use.
3. When the wound is filled with blood, deliver and pack the material loosely – do not compress.
4. To ensure tissue repair, fill the tissue defect with an adequate amount of collagen packed loosely.
5. After packing, perform simple suturing to prevent dislodgement.
6. Do not extend the material beyond the internal root margin line, so as not to interfere with epithelial formation.
7. Store at room temperature; do not reuse.
8. Contraindicated in patients with known allergy to bovine-derived materials or collagen products.
9. In GBR surgery, pack the material margins below the gingival margin; the centre can be exposed. Sutures should not be overly tightened to avoid compressing the wound.
10. In maxillary sinus lift surgery, do not roll or fold the material during packing to avoid impacting the sinus membrane.
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