SingJoint® is a colorless, transparent gel composed of hyaluronic acid derived from streptococcal fermentation metabolites.
It is indicated for the treatment of knee osteoarthritis symptoms. By replacing and supplementing the pathological synovial fluid in osteoarthritic joints, SingJoint® helps reduce pain and improve joint function. single-injection viscosupplement
01
Non animal-origin
non animal-origin ingredient, Singjoint contains the HA made by microbial fermentation technology
02
Effective
high concentration of the Singjoint will effectively reduce the pain of bone joint.
03
Safe
it's safe for bone joint to inject, leave no side effects to our bodies.
SingJoint® as a Synovial Fluid Replacement Injection
SingJoint® and SingJoint® Plus are both synovial fluid replacement injections, but they are formulated for different treatment protocols. SingJoint® uses a linear hyaluronic acid formulation delivered over 3 to 4 weekly injections, making it a cost-effective option for clinics offering a traditional multi-dose viscosupplementation course. SingJoint® Plus concentrates a higher total dose of hyaluronic acid into a single injection, offering the same 6-month-plus duration of relief with only one clinic visit. Choosing between the two is primarily a question of patient compliance, treatment cost, and clinic workflow. single-injection viscosupplement
The table below compares the two formulations so your team can match the right injection for synovial fluid replacement to each patient protocol.
specification
|
Features |
SingJoint® |
SingJoint® Plus |
|
Ingredient |
HA |
HA |
|
Source |
Biofermentation |
Biofermentation |
|
Molecular weight |
≥1.0 Mda |
≥1.6Mda |
|
Concentration |
10mg/ml, 12mg/ml |
20mg/ml |
|
Volume |
1.0ml, 2.0ml, 2.5ml |
2.0ml, 3.0ml |
|
Total HA Concentration |
10mg-30mg |
40mg, 60mg |
|
Type of HA configuration |
Linear |
Linear |
|
Monthly administration |
3 - 4 injection, once a week for 3 to 4 consecutive weeks. |
1 Injection |
|
Duration |
Up to 6 months |
6 months+ |
|
CE |
Yes |
Yes |
|
Safety |
Safe |
Safe |
|
Clinical studies |
Yes |
Yes |
|
Sales coverage |
90+ |
90+ |
As an injection for synovial fluid replacement, SingJoint® helps lubricate the joint, form a protective barrier, buffer stress, and inhibit inflammatory responses within the articular cavity. It stimulates the synovial membrane to produce high-molecular-weight sodium hyaluronate, alleviating joint pain, increasing mobility, reducing synovial inflammation, and slowing the progression of the disease.
SingJoint® has demonstrated long-lasting relief from osteoarthritis (OA) knee pain in clinical use. A study involving 300 participants with arthropathy was conducted at the First Affiliated Hospital of Zhejiang Chinese Medical University and Tongde Hospital of Zhejiang Province, two Grade A hospitals in China. Full study data is available on request for distributors and healthcare partners - contact our medical affairs team.
How to Use it?
Remove the Tip Cap: Remove the cap from the syringe and the needle tip.
Insert the Needle: Hold the syringe body and firmly insert the hub of the needle (select an appropriate puncture needle) into the luer-lock at the end of the syringe.
Tighten the Needle: Turn the needle clockwise until it is securely seated in the proper position.
Certification
SingJoint® and SingJoint® Plus are manufactured under ISO13485-certified quality systems, CE marked, and ANVISA registered. View our certificates.
To be Singclean's Distributor Partner!
As a fully integrated manufacturer of high-quality Singjoint Sodium Hyaluronate Injection, Singclean provides CE and ISO 13485-certified injections, trusted by orthopedic professionals around the globe. Our end-to-end manufacturing control ensures consistent supply, proven efficacy in osteoarthritis management, and excellent profit margins. With full regulatory support, including CE compliance, and robust partner-focused resources, we empower you to thrive in the joint care market. Expand your product line and make a lasting impact on patient outcomes with our innovative and reliable solutions.
FAQ
Q: How is Singjoint® given?
Q: What is the procedure like?
If joint effusion presents, it should be aspirated before performing the injection. Injection is only effective if the hyaluronic acid is delivered directly into the joint capsule of the knee (not the surrounding tissues).
Q: What are the adverse reactions of Singjoint® injections?
Q: What happens after the injections?
Q: Is SingJoint® an artificial synovial fluid injection?
A: Yes. SingJoint® is formulated to replace and supplement the pathological synovial fluid found in osteoarthritic knee joints, functioning as an artificial synovial fluid injection that restores lubrication and helps reduce friction during movement.
Q: What's the difference between a synovial fluid replacement injection and a steroid shot?
A: A synovial fluid replacement injection such as SingJoint® restores the viscoelastic properties of the joint's natural fluid and offers longer-lasting, chondroprotective relief. A steroid (cortisone) shot reduces inflammation quickly but only provides short-term relief and cannot be repeated frequently without risking cartilage damage.
Content reviewed by the Singclean Medical Affairs Team. Last updated: 2026.07.03.
This page is intended for healthcare professionals, distributors, and procurement teams. Clinical study details are available on request. This is not a substitute for professional medical advice.
Hot Tags: singjoint sodium hyaluronate injection for orthopedic surgery, China, manufacturers, suppliers, wholesale, gel shots in joints, nerve block injection for knee pain, hyaluronic injection for knee osteoarthritis, hyaluronic acid sodium salt, kit saliva, botox injections for smile lines
