SKformula Link® Crosslinked Hyaluronic Acid Skin Booster Injection
SKformula Link is a sterile, biodegradable, injectable slightly cross-linked implant indicated for injection into the dermis to improve skin appearance. Unlike traditional non-crosslinked HA skin boosters that require frequent touch-ups, SKformula Link features patented lightly crosslinked technology that extends the duration of effect while maintaining natural skin compatibility.
SKformula Link is indicated for injection into the dermis to improve skin appearance primarily through the moisturizing and hydrating effects of sodium hyaluronate. It is designed to:
Restore skin's hydro-balance
Improve skin structure and texture
Enhance elasticity
Reduce fine lines and wrinkles
Specification
| Concentration | 10 mg/mL Crosslinked Hyaluronic Acid |
| Available Sizes | 0.5mL, 1mL, 1.5mL, 2mL, 2.5mL, 3mL |
| Packaging | 3.0mL x 1pc prefilled syringe |
| Origin | Non-animal origin via bacterial fermentation |
| Target Layer | Dermis |
Clinical Efficacy & Mechanism of Action
How It Works
SKformula Link is implanted to supplement the intercellular matrix and intradermal tissue, restoring lost anatomical structures. Its mechanism of action is based on the latest biotechnological developments in injectable hyaluronic acid production.
The volume and lifting capacity originate from hyaluronic acid's ability to attract a high amount of water-a capability further enhanced by the crosslinking process. Sodium Hyaluronate is degraded in the body through the same metabolic pathway as endogenous hyaluronic acid, ensuring natural and safe absorption.
Duration of Effect
| Feature | Non-Crosslinked HA | Crosslinked HA (SKformula Link) |
|---|---|---|
| Molecular Structure | Linear, loose, fluid chains | Chemically crosslinked into stable 3D network |
| Texture | Low viscosity, spreads easily | Higher viscosity |
| Duration of Effect | Short: ~3 months | Long: 6 months or more |
| Primary Function | Hydration + skin brightness | Hydration + skin brightness + elasticity |
Treatment Protocol
Initial Course
Typically consists of 3 treatment sessions, spaced 4 weeks apart .
Maintenance
Optimal results lasting 6+ months. Repeat approximately every 6 months, though results and patient preferences vary.
Injection Guidelines
A combination of mechanical and manual injection is recommended for optimal results.
Mechanical Injection:
Use a mesotherapy device (e.g., Demasa mesotherapy injector)
Recommended injection depth: 0.8–1.5 mm
Needle gauge: 32G recommended
Maximum total dose per session: no more than 6 mL advised
Manual Injection:
Common techniques include linear threading, serial puncture injections, or a combination of both
Needle gauge: 27–32G recommended
Injection Sites
Whole face
Neck
Décolleté area
Backs of hands
Periorbital region (eye contour)
Product Advantages
1. World-Class HA Raw Material
Utilizes Kewpie Corporation's ultra-pure, non-animal medical-grade hyaluronic acid with extremely low impurities and endotoxins, outperforming comparable HA raw materials in multiple key indicators.
2. SingLin Patented Lightly Cross-Linking Technology
The lightly cross-linking technology enables HA to degrade significantly slower than non-crosslinked HA, thereby achieving long-lasting hydration. Simultaneously, it avoids excessive alteration of skin structure, mitigating long-term risks associated with over-crosslinking and maintaining compatibility with the skin's natural physiological state .
3. Monophasic Homogeneous Gel for Smoother Injection
Uniform, soft, and smooth texture ensures excellent injection feel and significantly reduces the risk of adverse events such as nodules.
4. Multiple Specifications for Personalized Needs
Available in various specifications to accommodate different treatment areas, dosages, and patient profiles, offering flexible options for tailored treatment plans.
5. High Safety Profile
Biological fermentation HA (non-animal origin)
Biodegradable and reversible with hyaluronidase
Significantly reduced endotoxins and foreign proteins
GMP Class 100k clean workshop manufacturing
Comparison: SKformula Link vs. Skin Boosters
| Feature | SKformula Link | Other Non-Crosslinked HA Skin Boosters |
|---|---|---|
| HA Structure | Crosslinked 3D network | Linear, non-crosslinked |
| Hydration Duration | 6+ months | ~3 months |
| Elasticity Improvement | Significant | Limited |
| Fine Line Reduction | Yes | Yes |
| Injection Frequency | Maintenance every 6 months | Repeat every 3 months |
| Patient Compliance | High (less frequent visits) | Lower (more frequent visits) |
Why Choose Singclean Medical?
Since establishment in 2003, Singclean Medical has been committed to being "the leading player in the field of absorbable biomaterials in the world" . With over 23 years of expertise in absorbable biomaterials, the company has effectively provided novel aesthetic solutions to global markets.
28,000 sqm
International intelligent manufacturing base
11 GMP clean workshops
including GMP Class 100k clean workshop
5,500 sqm
logistics center
3,000 sqm
R&D and quality inspection center
FAQ
Q: What is your minimum order quantity (MOQ)?
A: We offer flexible MOQ options for distributors, hospitals and OEM partners. Please contact our sales team for customized quotations based on your project requirements.
Q: Do you provide OEM or private label services?
A: Yes. We provide comprehensive OEM and private label services, including customized packaging, multilingual IFUs, branding, and registration documentation.
Q: Which certifications are available?
A: Depending on the destination market, SingJoint® is available with certifications such as CE, MHRA and ANVISA, supported by complete technical documentation.
Q: Can you support local product registration?
A: Yes. Our experienced regulatory affairs team supports distributors with technical files, certificates and registration documentation for many international markets.
Q: What is the production lead time?
A: Standard products are generally available within 7–15 working days, while OEM orders typically require 25–35 working days depending on customization requirements.
Q: Which countries have you exported to?
A: Singclean products are distributed in more than 80 countries and regions, with over 330 global strategic partners and local registrations in more than 50 countries.
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